Methylated-thiol-coenzyme M methyltransferase
From Wikipedia, the free encyclopedia
Methylated-thiol-coenzyme M methyltransferase (EC 2.1.1.251, mtsA (gene)) is an enzyme with systematic name methylated-thiol:coenzyme M methyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction:
| methanethiol + coenzyme M ⇌ methyl-CoM + hydrogen sulfide (overall reaction) | 1 |
| methanethiol + [Co(I) methylated-thiol-specific corrinoid protein] ⇌ [methyl-Co(III) methylated-thiol-specific corrinoid protein] + hydrogen sulfide | 1a |
| [methyl-Co(III) methylated-thiol-specific corrinoid protein] + coenzyme M ⇌ methyl-CoM + [Co(I) methylated-thiol-specific corrinoid protein] | 1b |
This enzyme involved in methanogenesis from methylated thiols, such as methanethiol, dimethyl sulfide, and 3-S-methylmercaptopropionate.
