Marple began her artist career as an intern at Blum & Poe and David Zwirner galleries. She worked as an artist assistant for the artist Karl Haendel and partnered with Davida Nemeroff on Night Gallery in 2011. While still at Night Gallery, she participated in art fairs like Frieze New York, Frieze London, Art Basel Hong Kong, and NADA Miami, and worked with artists like Sterling Ruby, Laura Owens, Samara Golden, and Josh Kline, among others.[citation needed]
Marple's art often combines new technologies, such as augmented reality and NFTs, with more traditional practices to create emotionally evocative experiences.[3][4] Her artwork has been exhibited at MOCA Westport,[5] the Museum of Contemporary Art in Zagreb, Croatia,[6] the Seattle NFT Museum,[7] and other arts galleries and platforms. Her work has been featured in The New York Times,[8]The Guardian,[9] Autre,[10] Fortune Magazine,[11] White Hot Magazine,[12] Flaunt,[13] and some others.
In 2014, Marple organized "Sexy Beast", a fundraiser for Planned Parenthood LA, with Davida Nemeroff.[14][15]
As a writer, Marple has published articles about arts and other topics with The Huffington Post,[16] Zyzzyva,[17] Lit Hub,[18]ARTnews,[19] Artsy
[20] and other media platforms.