Mir-101 microRNA precursor family
RNA family
From Wikipedia, the free encyclopedia
miR-101 microRNA precursor is a small non-coding RNA that regulates gene expression. Expression of miR-101 has been validated in both human (MI0000103[link removed], MI0000739)[1] and mouse (MI0000148[link removed]).[2] This microRNA appears to be specific to the vertebrates and has now been predicted or confirmed in a wide range of vertebrate species (MIPF0000046[link removed]). The precursor microRNA is a stem-loop structure of about 70 nucleotides in length that is processed by the Dicer enzyme to form the 21-24 nucleotide mature microRNA. In this case the mature sequence is excised from the 3' arm of the hairpin.
| mir-101 microRNA precursor family | |
|---|---|
Predicted secondary structure and sequence conservation of mir-101 | |
| Identifiers | |
| Symbol | mir-101 |
| Rfam | RF00253 |
| miRBase | MI0000103 |
| miRBase family | MIPF0000046 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain | Eukaryota |
| GO | GO:0035195 GO:0035068 |
| SO | SO:0001244 |
| PDB structures | PDBe |
Survival analysis shows that hsa-miR-101 is associated with survival in multiple breast cancer datasets.[3]
