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Mir-135 microRNA precursor family

RNA family From Wikipedia, the free encyclopedia

The miR-135 microRNA precursor is a small non-coding RNA that is involved in regulating gene expression. It has been shown to be expressed in human, mouse and rat.[1][2] miR-135 has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000028). Precursor microRNAs are ~70 nucleotides in length and are processed by the Dicer enzyme to produce the shorter 21-24 nucleotide mature sequence. In this case the mature sequence is excised from the 5' arm of the hairpin.

Quick facts Identifiers, Symbol ...
mir-135 microRNA precursor family
Identifiers
Symbolmir-135
RfamRF00246
miRBaseMI0000452
miRBase familyMIPF0000028
Other data
RNA typeGene; miRNA
DomainEukaryota
GOGO:0035195 GO:0035068
SOSO:0001244
PDB structuresPDBe
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Targets of miR-135

  • Nagel et al.. showed that miR-135a and b target the 3' untranslated region of the APC gene.[3]

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