Mir-633 microRNA precursor family
From Wikipedia, the free encyclopedia
| mir-633 | |
|---|---|
| Identifiers | |
| Symbol | mir-633 |
| Rfam | RF01028 |
| miRBase family | MIPF0000546 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-633 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
miR-633 has been linked to acute lymphoblastic leukaemia (ALL) and as having a potential role in the development of leukaemia, due to abnormal expression in ALL subjects.[1] It may be of use for prediction of relapse potential and in development of personalised leukaemia treatments.
Progesterone regulation
miR-633 expression in endometrial carcinoma cells upon treatment with progesterone saw a 50% decrease in expression levels. These point towards a possible critical role of miR-633, alongside other miRNAs, in the regulation of posttranscriptional gene expression on progesterone treatment.[2]
