Miyaura borylation
Chemical reaction
From Wikipedia, the free encyclopedia
Miyaura borylation, also known as the Miyaura borylation reaction, is a named reaction in organic chemistry that allows for the generation of boronates from vinyl or aryl halides with the cross-coupling of bis(pinacolato)diboron in basic conditions with a catalyst such as PdCl2(dppf). The resulting borylated products can be used as coupling partners for the Suzuki reaction.[1]
| Miyaura borylation | |
|---|---|
| Named after | Norio Miyaura |
| Reaction type | Organic redox reaction |
| Identifiers | |
| Organic Chemistry Portal | miyaura-borylation-reaction |
Scope
The Miyaura borylation has shown to work for:
Alkyl halides,[2] aryl halides,[1][3][4] aryl halides using tetrahydroxydiboron,[5] aryl halides using bis-boronic acid,[6] aryl triflates,[7] aryl mesylates,[8] vinyl halides,[9] vinyl halides of α,β-unsaturated carbonyl compounds,[10] and vinyl triflates.[11]