Ohno attended the Osaka University of Arts, she had become inspired to become an animator after watching Neon Genesis Evangelion.[4] She first began working with cardboard during a stop motion animation assignment. Wanting to save money, she began working with the cardboard boxes that her Amazon orders arrived in.[5] Her work received positive feedback and she began to focus on creating more cardboard sculptures.[4][6]
Originally Ohno's work was flat, as she struggled to produce 3D shapes out of the material. But as her skills developed, the scale and complexity of the figures grew.[4] When beginning a work, she draws a rough sketch on cardboard to figure out the scale before cutting out the design. When assembling her sculptures she uses glue and water to help shape cardboard.[2] To create depth in her sculptures Ohno cuts the surface layer of the cardboard, exposing the corrugated inside.[7]
In 2023 her work was featured in The Hidden World of Stationery Art exhibition held in Nihombashi Takashimaya Shopping Center.[8]
In 2024 a solo exhibition of her work was held at the Kaiyodo Space Factory Nankoku.[9] Another solo exhibition was held in May, in Kichijoji, Tokyo.[10]