Monica Bertagnolli

American surgical oncologist (born 1959) From Wikipedia, the free encyclopedia

Monica M. Bertagnolli (born 1959) is an American surgical oncologist who was the 17th director of the National Institutes of Health. She previously served as the 16th director of the National Cancer Institute (NCI).[1] Prior to her governmental positions, she worked at Brigham and Women's Hospital and Dana–Farber Cancer Institute and was the Richard E. Wilson Professor of Surgery at Harvard Medical School.[2]

PresidentJoe Biden
Preceded byFrancis Collins
Succeeded byJay Bhattacharya
Quick facts 17th Director of the National Institutes of Health, President ...
Monica Bertagnolli
Portrait photograph of Dr. Monica Bertagnolli
Bertagnolli in 2023
17th Director of the National Institutes of Health
In office
November 9, 2023  January 17, 2025
PresidentJoe Biden
DeputyLawrence A. Tabak
Preceded byFrancis Collins
Succeeded byJay Bhattacharya
16th Director of the National Cancer Institute
In office
October 3, 2022  November 9, 2023
PresidentJoe Biden
DeputyDouglas R. Lowy
Preceded byNorman Sharpless
Succeeded byKimryn Rathmell
Personal details
Born1959 (age 6667)
EducationPrinceton University (BS)
University of Utah (MD)
Scientific career
FieldsSurgical oncology
Gastrointestinal cancer
Adenomatous polyposis coli
Colorectal cancer
InstitutionsDana–Farber Cancer Institute
Harvard Medical School
NewYork-Presbyterian Hospital
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She has advocated for inclusion of rural communities in clinical studies and served as Chair of the Alliance for Clinical Trials in Oncology until her appointment to lead the NCI.[3] Bertagnolli specializes in the treatment of tumors from gastrointestinal diseases and soft tissue sarcomas.[4] She is the former President of the American Society of Clinical Oncology and was inducted into the National Academy of Medicine in 2021.[5][6]

Early life and education

Bertagnolli grew up on a cattle ranch in Wyoming.[7] Her parents were first generation Italian and French Basque immigrants.[8][9] She earned a BSE in biochemical engineering from Princeton University.[10][11] She studied medicine at the University of Utah School of Medicine and did her surgical residency at Brigham and Women's Hospital. She became board certified in 1993.[12]

Cancer research

In 1994, Bertagnolli began as an associate surgeon at the Strang Cancer Prevention Center and attending surgeon at NewYork-Presbyterian HospitalCornell.[10] She joined the faculty at Harvard Medical School in 1999 and was appointed at Dana–Farber Cancer Institute in 2000.[10] Bertagnolli specializes in the treatment of tumors from gastrointestinal diseases and is an expert in treating soft-tissue sarcoma.[8] She became the Chief of Surgical Oncology at the Dana–Farber Cancer Institute in 2007, and was the first woman to hold such a position.[8] Bertagnolli's laboratory at the Dana-Farber / Harvard Cancer Center studies the role of Adenomatous polyposis coli (APC) mutations in colorectal carcinogenesis through animal studies and human clinical trials.[13]

Selected publications

  • Sanford D Markowitz; Monica M Bertagnolli (December 17, 2009). "Molecular origins of cancer: Molecular basis of colorectal cancer". The New England Journal of Medicine. 361 (25): 2449–60. doi:10.1056/NEJMRA0804588. ISSN 0028-4793. PMC 2843693. PMID 20018966. Wikidata Q24617331.
  • Solomon SD; McMurray JJ; Pfeffer MA; et al. (March 17, 2005). "Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention". The New England Journal of Medicine. 352 (11): 1071–80. doi:10.1056/NEJMOA050405. ISSN 0028-4793. PMID 15713944. Wikidata Q29620087.
  • Itay Tirosh; Benjamin Izar; Sanjay M Prakadan; et al. (April 1, 2016). "Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq". Science. 352 (6282): 189–196. doi:10.1126/SCIENCE.AAD0501. ISSN 0036-8075. PMC 4944528. PMID 27124452. Wikidata Q37094024.

NIH director

In May 2023, President Biden nominated Bertagnolli to serve as the director of the National Institutes of Health.[14] Dr. Bertagnolli was confirmed by the United States Senate on November 7, 2023. She was the second woman director of the NIH.[15] She resigned at the end of President Biden's term.[16]

Awards and honors

Bertagnolli's awards and honors include:

Personal life

Bertagnolli is married and has two sons.[8] After a routine mammogram, Bertagnolli received an early-stage breast cancer diagnosis in November 2022.[22]

References

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