Monocyclic monoterpene ketone monooxygenase

Class of enzymes From Wikipedia, the free encyclopedia

Monocyclic monoterpene ketone monooxygenase (EC 1.14.13.105, 1-hydroxy-2-oxolimonene 1,2-monooxygenase, dihydrocarvone 1,2-monooxygenase, MMKMO) is an enzyme with systematic name (-)-menthone,NADPH:oxygen oxidoreductase.[1][2] This enzyme catalyses the several chemical reaction, for example the conversion of (–)-menthone to mentholactone:[3]

+ NADPH + H+
 
 
O2
H2O
Rightward reaction arrow with minor substrate(s) from top left and minor product(s) to top right
 
 
 
2D representation of the chemical structure of Q27122000.
mentholactone
 

This enzyme is a flavoprotein of Baeyer-Villiger monooxygenase type, which uses molecular oxygen as oxidant and incorporates one of its atoms into the starting material. It can act on a variety of monoterpene ketones and cyclohexanones.[3][4]

References

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