Monolysocardiolipin

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Chemical structure of MLCL backbone

Monolysocardiolipin (MLCL) is a phospholipid with three fatty acid chains located in the inner membrane of mitochondria.

MLCL is normally present as part of the metabolic cycle of mitochondrial lipids, such as cardiolipin.[1] It is remodeled by the enzymes monolysocardiolipin acyltransferase, lysocardiolipin acyltransferase, and tafazzin, which transfer a fourth fatty acid chain onto the phospholipid.[2]

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