Moriel Zelikowsky

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KnownforNeural circuits underlying fear and stress
AwardsNARSAD Young Investigator Award, LOREAL for Women in Science Award, Sloan 2020 Award in Neuroscience
Moriel Zelikowsky
Alma materUniversity of California, Los Angeles
Known forNeural circuits underlying fear and stress
AwardsNARSAD Young Investigator Award, LOREAL for Women in Science Award, Sloan 2020 Award in Neuroscience
Scientific career
InstitutionsUniversity of Utah School of Medicine
Websitehttps://www.zelikowskylab.com/

Moriel Zelikowsky is a neuroscientist at University of Utah School of Medicine. Her laboratory studies the brain circuits and neural mechanisms underlying stress, fear, and social behavior. Her previous work includes fear and the hippocampus, and the role of neuropeptide Tac2 in social isolation.

Zelikowsky was raised in Los Angeles and earned her bachelor's degree in Philosophy in 2006 from UCLA.[1] Originally, Zelikowsky started out as a film major until she took a few metaphysics classes. After deciding she was more interested in tangible answers to questions such as "what is the brain?" or "how do we think?" that she asked during philosophy classes, she started taking neuropsychiatry classes and applied to P.h.D programs in Psychology.[2] She joined the laboratory of Dr. Michael Fanselow at UCLA, which studies behavioral neuroscience, specifically fear learning and how fear memories are stored in the brain.[3] Her thesis work showed that a dynamic circuit composed of the amygdala, hippocampus, and prefrontal cortex contributes to fear learning and extinction in a context-sensitive manner.[4] Her work was published in the Journal of Neuroscience and was awarded the New York Academy of Sciences Cattell Award[5] and the Gengerelli Distinguished Dissertation Award.[6] She received her P.h.D in 2012.

Career and research

After receiving her P.h.D, Zelikowsky worked a postdoctoral fellow in the lab of Dr. David J. Anderson in the Department of Biology and Biological Engineering at Caltech.[6] Her work investigated how trauma and chronic stress are represented in the brain, and how neurons in these regions affect the impact of future stress on emotions and social behavior. Zelikowsky and colleagues in the Anderson lab identified a population of neuromodulators involved in stress regulation.[7] In an interview with L'Oréal USA For Women in Science, Zelikowsky explained "The brain undergoes significant change following an intense emotional event, and these alterations in neural processing and dynamics give rise to maladaptive behaviors. It is my hope that my research will contribute to a global shift towards increased cellular precision in our approach towards the treatment of mental health disorders".[8] A significant portion of this research focused specifically on social isolation and Tac2 and its influence on behavior.[9] As a postdoctoral fellow, Zelikowsky was supported by multiple awards and fellowships, including the National Science Foundation, a NARSAD Young Investigator Award,[10] a LOREAL for Women in Science Award,[8] and a NIMH K99/R00 Pathway to Independence Award.[11][12][6]

In the fall of 2019, Zelikowsky started her own lab at the University of Utah School of Medicine as an Assistant Professor in the Department of Neurobiology and Anatomy. Research projects in the lab include prolonged social isolation, post traumatic stress disorder, the intersection or memory and social behavior, and stress and mating.[13] Zelikowsky was recently awarded a 2020 Sloan Research Fellowship in recognition of "creativity, leadership, and achievements in research".[14]

In addition to her research, Zelikowsky also founded a group called Women in Learning which aims to provide a way for students and postdoctoral fellows studying learning, behavior, memory, and the broader field of neuroscience to find support and guidance on the promotion of female researchers from notable women already established in the field.[15]

Publications

Awards and honors

References

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