Mycobacterium bohemicum
From Wikipedia, the free encyclopedia
| Mycobacterium bohemicum | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Bacillati |
| Phylum: | Actinomycetota |
| Class: | Actinomycetes |
| Order: | Mycobacteriales |
| Family: | Mycobacteriaceae |
| Genus: | Mycobacterium |
| Species: | M. bohemicum |
| Binomial name | |
| Mycobacterium bohemicum Reischl et al. 1998, CIP 105808 | |
Mycobacterium bohemicum is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.
Mycobacterium bohemicum is a nontuberculous bacterium that has been isolated from human tissue, animals, and the environment. M. bohemicum affects soft tissue in animal cells.[1] Mycobacterium bohemicum was identified in 1998 when isolated from sputum that was produced by a 53-year-old Down's Syndrome patient with tuberculosis[2] M. bohemicum has been reported and documented in 9 patients worldwide.[3] Reports of the bacterium have been recorded from Finland and Austria. In children, M. bohemicum has induced laterocervical and submandibular lymphadenitis.[4] The excision of the subject's lymph nodes along with antimicrobial therapy increased the health of the subjects in less than 12 months.[1]
The lymph nodes of the subjects were minced and stained according to the Ziehl–Neelsen technique.[5] Within 12–17 days a culture was produced that could be analyzed on a molecular level "Richter". M. bohemicum contains combinations of α-, keto-, metoxy-, and dicarboxy-mycolates that are not commonly found in slow-growing bacteria [3]. Other distinct characteristics of M. bohemicum is identifiable by its unique 16S rDNA nucleotide sequence as well as its variation in the ITS sequence region of 16S-23S.[6]
- Sensitive to compounds such as prothionamide, cycloserine, clarithromycin, gentamicin, amikacin.[1]
- Resistant to compounds such as isoniazid, streptomycin, ethambutol, rifampin, and ciprofloaxin.[1]
- Optimum temperature is around 37 degrees Celsius.[1]
- Enzymatic activity- weak positive test for urease.[1]