N-Methyl-PPPA

N-Methyl-PPPA, or N-methyl-3-phenoxy-3-phenylpropan-1-amine, is a serotonin-norepinephrine reuptake inhibitor (SNRI) which was developed by Eli Lilly from diphenhydramine in the early 1970s while in search of new antidepressants, but was never marketed.^[1][2][3] It is closely related structurally to fluoxetine, atomoxetine, and nisoxetine.^[1][2][3]

Other namesDetrifluoromethylfluoxetine

ATC code

• None

CAS Number

• 56161-70-7

PubChem CID

• 15894873

Quick facts Clinical data, Other names ...

N-Methyl-PPPA

Clinical data
Other names	Detrifluoromethylfluoxetine
ATC code	None
Identifiers
IUPAC name N-Methyl-3-phenoxy-3-phenyl-1-propanamine
CAS Number	56161-70-7
PubChem CID	15894873
ChemSpider	16340904
UNII	C6C3GB68TV
ChEMBL	ChEMBL4865485
CompTox Dashboard (EPA)	DTXSID001289081
Chemical and physical data
Formula	C16H19NO
Molar mass	241.334 g·mol−1
3D model (JSmol)	Interactive image
SMILES CNCCC(Oc1ccccc1)c2ccccc2
InChI InChI=1S/C16H19NO/c1-17-13-12-16(14-8-4-2-5-9-14)18-15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3 Key:DMOUAPYFRKLFHO-UHFFFAOYSA-N

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