NBoc-DMT

NBoc-DMT, or NB-DMT, also known as N¹-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family.^[1][2] It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′-tert-butyloxycarbonyl (NBoc) group.^[1][2]

Other namesNB-DMT; DMT-BOC; N′-t-BOC-DMT; N′-tert-BOC-DMT; tert-BOC-DMT; N′-tert-Butoxycarbonyl-N,N-dimethyltryptamine

Drug classSerotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT_2A receptor agonist

Legal status

• Illegal in Russia

CAS Number

• 2210243-51-7

Quick facts Clinical data, Other names ...

NBoc-DMT

Clinical data
Other names	NB-DMT; DMT-BOC; N′-t-BOC-DMT; N′-tert-BOC-DMT; tert-BOC-DMT; N′-tert-Butoxycarbonyl-N,N-dimethyltryptamine
Drug class	Serotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist
Legal status
Legal status	Illegal in Russia
Identifiers
IUPAC name tert-butyl 3-[2-(dimethylamino)ethyl]-1H-indole-1-carboxylate
CAS Number	2210243-51-7
PubChem CID	141803940
Chemical and physical data
Formula	C17H24N2O2
Molar mass	288.391 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CCN(C)C
InChI InChI=1S/C17H24N2O2/c1-17(2,3)21-16(20)19-12-13(10-11-18(4)5)14-8-6-7-9-15(14)19/h6-9,12H,10-11H2,1-5H3 Key:IKVMWFRRDDILJA-UHFFFAOYSA-N

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NB-DMT is said to be a "prodrug" of DMT that decomposes into DMT when the compound is heated (e.g., with smoking or vaping).^[1] It may also be useful as an orally active prodrug of DMT, unlike DMT itself which is inactive when taken orally.^[3][4] NB-DMT has been claimed to have about 25% of the potency of DMT by weight.^[1] It was first detected as a designer drug being sold online by February 2024.^[1]

NB-DMT is a Schedule I controlled substance in Russia.^[1] The drug is not an explicitly controlled substance in the United States^[5] or in Canada.^[6] A number of other NBoc designer drugs have also been encountered.^[1][7]