NCKAP1

NCKAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P8C, 4N78
Identifiers
Aliases	NCKAP1, HEM2, NAP1, NAP125, p125Nap1, NCK associated protein 1
External IDs	OMIM: 604891; MGI: 1355333; HomoloGene: 8384; GeneCards: NCKAP1; OMA:NCKAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	183,038,858 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	80,411,724 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; frontal pole; ; skin of arm; ; Epithelium of choroid plexus; ; cerebellar vermis; ; ganglionic eminence; ; ventricular zone; ; lateral nuclear group of thalamus; ; oral cavity; ; orbitofrontal cortex;
	Top expressed in
	CA3 field; ; Region I of hippocampus proper; ; cingulate gyrus; ; dorsal striatum; ; amygdala; ; hippocampus proper; ; primary motor cortex; ; substantia nigra; ; central gray substance of midbrain; ; nucleus of stria terminalis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-containing complex binding; protein binding;
Cellular component	integral component of membrane; cytosol; cell projection; membrane; SCAR complex; focal adhesion; plasma membrane; extracellular exosome; lamellipodium membrane; ruffle; lamellipodium; filamentous actin;
Biological process	Fc-gamma receptor signaling pathway involved in phagocytosis; positive regulation of Arp2/3 complex-mediated actin nucleation; central nervous system development; vascular endothelial growth factor receptor signaling pathway; Rac protein signal transduction; viral process; apoptotic process; positive regulation of lamellipodium assembly; positive regulation of actin filament polymerization; cell morphogenesis; cell migration; cell projection assembly; cortical actin cytoskeleton organization; neuron projection morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	10787
	50884
	ENSG00000061676
	ENSMUSG00000027002
	Q9Y2A7
	P28660
	NM_013436; NM_205842
	NM_001290745; NM_016965; NM_001355410; NM_001355411
	NP_038464; NP_995314
	NP_001277674; NP_058661; NP_001342339; NP_001342340
	Wikidata
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