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NDTDI

Chemical compound From Wikipedia, the free encyclopedia

NDTDI, also known as 9-desmethine-LSD, 9-nor-LSD, or 8,10-seco-LSD, is a psychedelic drug related to lysergic acid diethylamide (LSD).[1][2][3][4] It is a tricyclic cyclized tryptamine and partial lysergamide and is a structurally simplified analogue of LSD.[2] The drug is specifically the analogue of LSD in which the carbon atom at position 9 of the ergoline ring system has been removed.[2] It has been reported to produce psychedelic effects similarly to LSD, but with much lower potency.[1] The pharmacology of NDTDI has not been studied. NDTDI was encountered as a novel designer drug by 2016.[1][3][4]

Structures of LSD (left), NDTDI (4-desmethine-LSD) (middle), and N-DEAOP-NMT (desvinyl-LSD) (right).
Other namesN-(2-Diethylcarbamoylethyl)-N-methyl-4,α-methylenetryptamine; N-(3-Diethylamino-3-oxopropyl)-N-methyl-4,α-methylenetryptamine; 9-Nor-LSD; 9-Desmethine-LSD; 8,10-Seco-LSD
ATC code
  • None
Legal status
  • Illegal in Latvia
Quick facts Clinical data, Other names ...
NDTDI
Clinical data
Other namesN-(2-Diethylcarbamoylethyl)-N-methyl-4,α-methylenetryptamine; N-(3-Diethylamino-3-oxopropyl)-N-methyl-4,α-methylenetryptamine; 9-Nor-LSD; 9-Desmethine-LSD; 8,10-Seco-LSD
Drug classSerotonergic psychedelic; Hallucinogen; Simplified/partial LSD analogue
ATC code
  • None
Legal status
Legal status
  • Illegal in Latvia
Identifiers
  • N,N-diethyl-3-(methyl(1,3,4,5-tetrahydrobenzo[cd]indol-4-yl)amino)propanamide
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H27N3O
Molar mass313.445 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)CCN(C)C1Cc3cccc2ncc(C1)c23
  • InChI=1S/C19H27N3O/c1-4-22(5-2)18(23)9-10-21(3)16-11-14-7-6-8-17-19(14)15(12-16)13-20-17/h6-8,13,16,20H,4-5,9-12H2,1-3H3
  • Key:JECGWOMOCPQHDH-UHFFFAOYSA-N
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Interactions

Chemistry

Analogues

Analogues of NDTDI include RU-27849, RU-28306, RU-28251, Bay R 1531 (LY-197206), LY-293284, and LY-178210. Other partial/simplified lysergamides include DEIMDHPCA (4-nor-LSD), DEMPDHPCA (dides-B,C-LSD), and 10,11-seco-LSD, among others. Deletion of the carbon at positions 9 and 10 of the ergoline ring system result in a fully non-rigid tryptamine derivative, N-DEAOP-NMT (9,10-dinor-LSD).[5][6]

History

NDTDI has been sold as a designer drug since 2016 and was first identified by a forensic laboratory in Slovenia in 2017.[3] NDTDI was made illegal in Latvia in March 2017.[4][7]

Society and culture

Canada

NDTDI is not an explicitly nor implicitly controlled substance in Canada as of 2025.[8]

United States

NDTDI is not an explicitly controlled substance in the United States.[9] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

See also

References

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