NDTDI
Chemical compound
From Wikipedia, the free encyclopedia
NDTDI, also known as 9-desmethine-LSD, 9-nor-LSD, or 8,10-seco-LSD, is a psychedelic drug related to lysergic acid diethylamide (LSD).[1][2][3][4] It is a tricyclic cyclized tryptamine and partial lysergamide and is a structurally simplified analogue of LSD.[2] The drug is specifically the analogue of LSD in which the carbon atom at position 9 of the ergoline ring system has been removed.[2] It has been reported to produce psychedelic effects similarly to LSD, but with much lower potency.[1] The pharmacology of NDTDI has not been studied. NDTDI was encountered as a novel designer drug by 2016.[1][3][4]

- None
- Illegal in Latvia
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| Other names | N-(2-Diethylcarbamoylethyl)-N-methyl-4,α-methylenetryptamine; N-(3-Diethylamino-3-oxopropyl)-N-methyl-4,α-methylenetryptamine; 9-Nor-LSD; 9-Desmethine-LSD; 8,10-Seco-LSD |
| Drug class | Serotonergic psychedelic; Hallucinogen; Simplified/partial LSD analogue |
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| Formula | C19H27N3O |
| Molar mass | 313.445 g·mol−1 |
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Interactions
Chemistry
Analogues
Analogues of NDTDI include RU-27849, RU-28306, RU-28251, Bay R 1531 (LY-197206), LY-293284, and LY-178210. Other partial/simplified lysergamides include DEIMDHPCA (4-nor-LSD), DEMPDHPCA (dides-B,C-LSD), and 10,11-seco-LSD, among others. Deletion of the carbon at positions 9 and 10 of the ergoline ring system result in a fully non-rigid tryptamine derivative, N-DEAOP-NMT (9,10-dinor-LSD).[5][6]
History
NDTDI has been sold as a designer drug since 2016 and was first identified by a forensic laboratory in Slovenia in 2017.[3] NDTDI was made illegal in Latvia in March 2017.[4][7]
Society and culture
Legal status
Canada
NDTDI is not an explicitly nor implicitly controlled substance in Canada as of 2025.[8]
United States
NDTDI is not an explicitly controlled substance in the United States.[9] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.