NF-56-EJ40

CAS Number

• 2380230-73-7

PubChem CID

• 138811017

IUPHAR/BPS

• 10519

ChemSpider

• 84421867

NF-56-EJ40

Identifiers
IUPAC name 2-(2-(4'-((4-Methylpiperazin-1-yl)methyl)-[1,1'-biphenyl]-3-carboxamido)phenyl)acetic acid
CAS Number	2380230-73-7
PubChem CID	138811017
IUPHAR/BPS	10519
ChemSpider	84421867
ChEMBL	ChEMBL4790324
Chemical and physical data
Formula	C27H29N3O3
Molar mass	443.547 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1CCN(CC1)CC2=CC=C(C=C2)C3=CC(=CC=C3)C(=O)NC4=CC=CC=C4CC(=O)O
InChI InChI=1S/C27H29N3O3/c1-29-13-15-30(16-14-29)19-20-9-11-21(12-10-20)22-6-4-7-24(17-22)27(33)28-25-8-3-2-5-23(25)18-26(31)32/h2-12,17H,13-16,18-19H2,1H3,(H,28,33)(H,31,32) Key:UTWXDNZWMQAUKL-UHFFFAOYSA-N

NF-56-EJ40 is an experimental drug which acts as a potent and selective antagonist for the succinate receptor SUCNR1 (GPR91). It has antiinflammatory effects and has been used to investigate the role of succinate in the development of conditions such as atherosclerosis and ulcerative colitis.^[1][2][3][4]