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NKTR

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

NK-tumor recognition protein is a protein that in humans is encoded by the NKTR gene.[5][6][7]

AliasesNKTR, p104, natural killer cell triggering receptor
External IDsOMIM: 161565; MGI: 97346; GeneCards: NKTR
PDBOrtholog search: PDBe RCSB
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NKTR
Identifiers
AliasesNKTR, p104, natural killer cell triggering receptor
External IDsOMIM: 161565; MGI: 97346; GeneCards: NKTR
Available structures
PDBOrtholog search: PDBe RCSB
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
5.2.1.8↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001012651
NM_005385
NM_001349124
NM_001349125
NM_001349126

NM_010918

RefSeq (protein)

NP_005376
NP_001336053
NP_001336054
NP_001336055

NP_035048

Location (UCSC)Chr 3: 42.6 – 42.65 MbChr 9: 121.72 – 121.76 Mb
PubMed search[3][4]
Wikidata
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This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells.[7]

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