NPAT (gene)

AliasesNPAT, E14, E14/p220, nuclear protein, co-activator of histone transcription, nuclear protein, coactivator of histone transcription

External IDsOMIM: 601448; MGI: 107605; HomoloGene: 1888; GeneCards: NPAT; OMA:NPAT - orthologs

Chr.Chromosome 11 (human)^[1]

End108,222,638 bp^[1]

NPAT
Identifiers
Aliases	NPAT, E14, E14/p220, nuclear protein, co-activator of histone transcription, nuclear protein, coactivator of histone transcription
External IDs	OMIM: 601448; MGI: 107605; HomoloGene: 1888; GeneCards: NPAT; OMA:NPAT - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q22.3 Start 108,157,215 bp[1] End 108,222,638 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 A5.3|9 29.12 cM Start 53,448,347 bp[2] End 53,485,642 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte Achilles tendon testicle endothelial cell visceral pleura gonad parietal pleura epithelium of colon tibia tonsil Top expressed in hand Gonadal ridge primitive streak external carotid artery superior cervical ganglion otolith organ utricle substantia nigra genital tubercle trigeminal ganglion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription coactivator activity protein C-terminus binding protein binding transcription corepressor activity protein N-terminus binding transcription coregulator activity Cellular component cytoplasm Cajal body nucleus gemini of coiled bodies nucleoplasm Biological process regulation of gene expression positive regulation of transcription, DNA-templated cell cycle regulation of transcription, DNA-templated regulation of transcription involved in G1/S transition of mitotic cell cycle transcription, DNA-templated negative regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4863 244879 Ensembl ENSG00000149308 ENSMUSG00000033054 UniProt Q14207 Q8BMA5 RefSeq (mRNA) NM_002519 NM_001321307 NM_001081152 NM_178905 RefSeq (protein) NP_001308236 NP_002510 NP_001074621 Location (UCSC) Chr 11: 108.16 – 108.22 Mb Chr 9: 53.45 – 53.49 Mb PubMed search [3] [4]
Wikidata
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Protein NPAT also known as nuclear protein of the ATM locus is a protein that in humans is encoded by the NPAT gene.^[5][6]