Nagy Habib
Egyptian professor of surgery
From Wikipedia, the free encyclopedia
Nagy Habib (born 1952) is a British-Egyptian professor of hepato-biliary surgery at Imperial College, London, and is known for devising radio-frequency based liver resection devices which remove liver tumour with minimal blood loss. His work has also focused on stem cells and gene therapy.
Nagy Habib | |
|---|---|
Nagy Habib (2021) | |
| Born | 1952 (age 73–74) |
| Occupation | Surgeon |
| Known for | Radio-frequency based surgical devices |
| Medical career | |
| Profession | Liver surgeon |
| Institutions | Imperial College, London |
| Research |
|
Early life and education
Nagy Habib was born in Cairo, Egypt, 1952.[1] He trained under both Henri Bismuth and the transplant surgeon Thomas Starzl.[2]
Career
His work has focused on stem cells and gene therapy.[3] He led the first clinical trial in the use of oncolytic adenoviruses for the treatment of liver cancer.[4] It was carried out by means of a locally restricted injection into the main blood vessel to the liver.[5][6] The findings were published in 2001.[5][6] It was found to be safe, but the second phase of the trial did not find it effective.[5][6] In 2004, he took stem cells from a person with liver cirrhosis and injected them into their liver artery, resulting in some improvement of liver function.[7]
In 2003 he was appointed professor of hepato-biliary surgery at Imperial College, London.[8] In June 2007 he was appointed pro-rector for Commercial Affairs at Imperial.[4]
Habib developed several radio-frequency (RF) based liver resection devices.[9][10] He devised the Habib RF device using the Habib needle, which has a modified version called the Habib 4X.[10] It removes tumour with minimal blood loss.[10] The procedure has come to be known as 'Habib's resection'.[11]
MiNA Therapeutics, a biotechnology company dealing in small activating RNA technology was co-founded by Habib and his son Robert.[12]
Awards and honours
He was awarded the Takreem award in December 2012, for his work in liver cancer and radio-frequency based liver resection.[4]
Selected publications
Articles
- Habib, Nagy A.; Sarraf, Catherine E.; Mitry, Ragai R.; Havlík, Roman; Nicholls, Joanna; Kelly, Michael; Vernon, Clare C.; Gueret-Wardle, David; El-Masry, Rashad; Salama, Hosny; Ahmed, Rasha; Michail, Nagy; Edward, Ezzat; Jensen, Steen L. (10 February 2001). "E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors". Human Gene Therapy. 12 (3): 219–226. doi:10.1089/10430340150218369. ISSN 1043-0342. PMID 11177559. (Co-author)
- Habib, Nagy; Salama, Hosny; Abd El Latif Abu Median, Ahmed; Isac Anis, Ilia; Abd Al Aziz, Rasha Ahmed; Sarraf, Catherine; Mitry, Ragai; Havlik, Roman; Seth, Prem; Hartwigsen, Jack; Bhushan, Reva; Nicholls, Joanna; Jensen, Steen (March 2002). "Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma". Cancer Gene Therapy. 9 (3): 254–259. doi:10.1038/sj.cgt.7700431. ISSN 1476-5500. PMID 11896441. S2CID 42290755. (Co-author)
- Havlik, Roman; Jiao, Long R.; Nicholls, Joanna; Jensen, Steen Lindkaer; Habib, Nagy A. (April 2002). "Gene therapy for liver metastases". Seminars in Oncology. 29 (2): 202–208. doi:10.1053/sonc.2002.31678. ISSN 0093-7754. PMID 11951219. (Co-author)
- Ferko, A.; Leško, M.; Šubrt, Z.; Melichar, B.; Hoffman, P.; Dvořák, P.; Vacek, Z.; Liao, L.R.; Habib, N.A.; Kočí, J.; Motyčka, P. (December 2006). "A modified radiofrequency-assisted approach to right hemihepatectomy". European Journal of Surgical Oncology. 32 (10): 1209–1211. doi:10.1016/j.ejso.2006.07.013. PMID 16950592. (Co-author)
Books
- Hepatocellular Carcinoma: Methods and Protocols[. Totowa: Springer. 2000. ISBN 978-1-59259-079-7.