Nandrolone hexyloxyphenylpropionate

Nandrolone hexyloxyphenylpropionate
Clinical data
Trade names	Anador, Anadur, Anadurine
Other names	NHPP; 19-Nortestosterone 17β-(3-(4-hexyloxy)phenyl)propionate
Routes of; administration	Intramuscular injection
Drug class	Androgen; Anabolic steroid; Androgen ester; Progestogen
Pharmacokinetic data
Elimination half-life	Intramuscular: 20 days
Identifiers
	IUPAC name [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] 3-(4-hexoxyphenyl)propanoate;
CAS Number	52279-57-9 ;
PubChem CID	92341;
ChemSpider	83364;
UNII	602JJC2862;
CompTox Dashboard (EPA)	DTXSID20966654 ;
ECHA InfoCard	100.052.538
Chemical and physical data
Formula	C33H46O4
Molar mass	506.727 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCOC1=CC=C(C=C1)CCC(=O)O[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3CCC5=CC(=O)CC[C@H]45)C;
	InChI InChI=1S/C33H46O4/c1-3-4-5-6-21-36-26-12-7-23(8-13-26)9-18-32(35)37-31-17-16-30-29-14-10-24-22-25(34)11-15-27(24)28(29)19-20-33(30,31)2/h7-8,12-13,22,27-31H,3-6,9-11,14-21H2,1-2H3/t27-,28+,29+,30-,31-,33-/m0/s1; Key:PQKRYXHYWWQULJ-JMKYFRMNSA-N;

Nandrolone hexyloxyphenylpropionate (NHPP; brand names Anador, Anadur, Anadurine), also known as 19-nortestosterone 17β-(3-(4-hexyloxy)phenyl)propionate, is a synthetic androgen and anabolic steroid and a nandrolone ester that is marketed in France, Denmark, Austria, Luxembourg, and Turkey.^[3]^[4]^[5]^[6] It has been studied as a potential long-acting injectable male contraceptive, though it has not been marketed for this indication.^[7] Approximately 70% of men became azoospermic, while the remaining men all became oligospermic.^[7] NHPP has a mean residence time in the body of 29.1 days and an elimination half-life in the body of 20.1 days.^[1]

More information Compound, PRTooltip Progesterone receptor ...

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Relative affinities (%) of nandrolone and related steroids
Compound	PRTooltip Progesterone receptor	ARTooltip Androgen receptor	ERTooltip Estrogen receptor	GRTooltip Glucocorticoid receptor	MRTooltip Mineralocorticoid receptor	SHBGTooltip Sex hormone-binding globulin	CBGTooltip Transcortin
Nandrolone	20	154–155	<0.1	0.5	1.6	1–16	0.1
Testosterone	1.0–1.2	100	<0.1	0.17	0.9	19–82	3–8
Estradiol	2.6	7.9	100	0.6	0.13	8.7–12	<0.1
Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PRTooltip progesterone receptor, testosterone for the ARTooltip androgen receptor, estradiol for the ERTooltip estrogen receptor, dexamethasone for the GRTooltip glucocorticoid receptor, aldosterone for the MRTooltip mineralocorticoid receptor, dihydrotestosterone for SHBGTooltip sex hormone-binding globulin, and cortisol for CBGTooltip Transcortin. Sources: See template.

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Hormone levels with nandrolone esters by intramuscular injection

Nandrolone levels after a single 50, 100, or 150 mg intramuscular injection of nandrolone decanoate in oil solution in men.^[8]
Nandrolone levels after a single 100 mg intramuscular injection of nandrolone decanoate or nandrolone phenylpropionate in 4 mL or 1 mL arachis oil solution into gluteal or deltoid muscle in men.^[9]
Nandrolone levels with a single 50 mg intramuscular injection of nandrolone decanoate or nandrolone hexyloxyphenylpropionate in oil solution in men.^[10]
Dose-normalized nandrolone exposure (serum level divided by dose administered) with nandrolone decanoate in oil solution by intramuscular or subcutaneous injection in men.^[11]^[12]