Nef synthesis
From Wikipedia, the free encyclopedia
In organic chemistry, Nef synthesis is the addition of sodium acetylides to aldehydes and ketones to yield propargyl alcohols.[1][2][3][4][5][6] It is named for John Ulric Nef, who discovered the reaction in 1899.
| Nef synthesis | |
|---|---|
| Named after | John Ulric Nef |
| Reaction type | Coupling reaction |
| Identifiers | |
| RSC ontology ID | RXNO:0000506 |
This process is often erroneously referred to as the Nef reaction,[4][7][8][9] which is an unrelated chemical transformation discovered by the same chemist.
