Nelivaptan

Nelivaptan
Clinical data
Routes of; administration	Oral
ATC code	none;
Identifiers
	IUPAC name (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxo-indolin-3-yl]-4-hydroxy-N,N-dimethyl-pyrrolidine-2-carboxamide;
CAS Number	439687-69-1 ;
PubChem CID	9895468;
IUPHAR/BPS	2202;
ChemSpider	8071134 ;
UNII	3TY57MQ4OA;
ChEMBL	ChEMBL582857 ;
CompTox Dashboard (EPA)	DTXSID7047358 ;
ECHA InfoCard	100.210.987
Chemical and physical data
Formula	C30H32ClN3O8S
Molar mass	630.11 g·mol−1
	InChI InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1 ; Key:NJXZWIIMWNEOGJ-WEWKHQNJSA-N ;
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Nelivaptan (INN)^[1] (developmental codename SSR-149,415) is a selective, orally active, non-peptide vasopressin receptor antagonist selective for the V_1B subtype.^[2] The drug had entered clinical trials for treatment of anxiety and depression.^[3] In July 2008, Sanofi-Aventis announced that further development of this drug had been halted.^[4]

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Clinical data

Routes of administration	Oral
ATC code	none
Identifiers
IUPAC name (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxo-indolin-3-yl]-4-hydroxy-N,N-dimethyl-pyrrolidine-2-carboxamide
CAS Number	439687-69-1^N
PubChem CID	9895468
IUPHAR/BPS	2202
ChemSpider	8071134^Y
UNII	3TY57MQ4OA
ChEMBL	ChEMBL582857^Y
CompTox Dashboard (EPA)	DTXSID7047358
ECHA InfoCard	100.210.987
Chemical and physical data
Formula	C₃₀H₃₂ClN₃O₈S
Molar mass	630.11 g·mol⁻¹
InChI InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1^Y Key:NJXZWIIMWNEOGJ-WEWKHQNJSA-N^Y
^NY (what is this?) (verify)