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Neuropeptide Y receptor type 1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene.[5][6]

AliasesNPY1R, NPY1-R, NPYR, Neuropeptide Y receptor Y1
External IDsOMIM: 162641; MGI: 104963; GeneCards: NPY1R
PDBOrtholog search: PDBe RCSB
Quick facts NPY1R, Identifiers ...
NPY1R
Identifiers
AliasesNPY1R, NPY1-R, NPYR, Neuropeptide Y receptor Y1
External IDsOMIM: 162641; MGI: 104963; GeneCards: NPY1R
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000909

NM_010934
NM_001358955

RefSeq (protein)

NP_000900

NP_035064
NP_001345884

Location (UCSC)Chr 4: 163.32 – 163.34 MbChr 8: 67.15 – 67.16 Mb
PubMed search[3][4]
Wikidata
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Selective ligands

Agonists

Antagonists

Peptide
  • BVD-10 (selective NPY1 antagonist, CAS# 262418-00-8)
  • GR-231,118 (mixed NPY1 antagonist / NPY4 agonist, CAS# 158859-98-4)
Non-peptide
  • BIBO-3304 (CAS# 191868-14-1)
  • BIBP-3226 (CAS# 159013-54-4)
  • PD-160,170 (CAS# 181468-88-2)

Available Structures

  • 5ZBH (Neuropeptide Y1 bound to antagonist BMS-193835)[7]
  • 5ZBQ (Neuropeptide Y1 bound to antagonist UR-MK299)[7]

See also

References

Further reading

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