Nicotianamine synthase
Class of enzymes
From Wikipedia, the free encyclopedia
Nicotianamine synthase (EC 2.5.1.43) is an enzyme that catalyzes the chemical reaction
| Nicotianamine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.43 | ||||||||
| CAS no. | 161515-44-2 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme converts three units of its substrate, S-adenosyl methionine, into nicotianamine and three units of 5′-methylthioadenosine as a by-product.[1][2]
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-Lmethioni ne 3-amino-3-carboxypropyltransferase. Nicotianamine is a metal-chelating molecule ubiquitous in higher plants that assists in their uptake of metals from soil.[3][4]
