Niveen Khashab
From Wikipedia, the free encyclopedia
Niveen M. Khashab is a Lebanese chemist and a Professor of chemical Sciences and engineering at King Abdullah University of Science and Technology in Saudi Arabia since 2009.[1][2] She is a laureate of the 2017 L'Oréal-UNESCO Awards for Women in Science "for her contributions to innovative smart hybrid materials aimed at drug delivery and for developing new techniques to monitor intracellular antioxidant activity."[3] She is also a fellow of the Royal Chemical Society, and a member of the American Chemical Society.[4]
Niveen M. Khashab received her B.S. in Chemistry from the American University of Beirut, Lebanon, followed by her PhD in chemistry at the University of Florida.[5][6]
Research & Career
Professor Khashab's research focuses on the design, synthesis, and use of "smart" programmable nanomaterials, emphasizing the systems' controlled release and delivery characteristics.[7][8][9] These synthetic materials are applied for biomimetic biological (distribution, sensing, and imaging), industrial (nanocomposites), and environmental (synthesis of membranes) applications, respectively.[10][11][12][13] Niveen's research interests include leveraging the natural microporosity of supramolecular assemblies for energy-intensive separations. Her research team is particularly interested in the separation of benzene derivatives employing macrocycles and cages designed for optimal separation via molecular recognition.[14] Her team has produced a variety of self-assembled capsules (SACs) for the encapsulation and transport of RNA, DNA, and proteins. She focuses on the encapsulation and delivery of CRISPR-Cas9 to enhance targeted gene editing.[15][16]
With more than ten years of professional experience, Prof. Niveen M. Khashab is presently a Full Professor and Head of the Chemistry Program at the King Abdullah University of Science and Technology.
Bibliography
- Carbon Nanomaterials Sourcebook: Graphene, Fullerenes, Nanotubes, and Nanodiamonds, Volume I.[17]
Patents
Prof. Niveen M. Khashab has obtained many patents for her inventions including:
- Compositions of graphene materials with metal nanostructures and microstructures and methods of making and using including pressure sensors (US10807048B2)[18]
- Magnetically controlled permeability membranes (US20180296469A1)[19]
- Periodic mesoporous organosilica-doped nanocomposite membranes and systems including same (EP3471864A1)[20]
- Nanocluster capped mesoporous nanoparticles, methods of making and use (US20200046849A1)[21]
- Polymer carbon nanotube composite (US20160297952A1)[22]
- Polymer nanocomposites and methods of making nanocomposites (US9650494B2)[23]
- Separating aromatic isomers using aqueous solutions of cucurbituril macrocycles (WO2021124219A1)[24]
- Periodic mesoporous organosilica-doped nanocomposite membranes and systems including same (US20200306701A1)[25]
- Encoding Raman spectral data in optical identification tags for analyte identification (WO2021053409A1)[26]
Publications
- Jonas G. Croissant, Yevhen Fatieiev, Niveen M. Khashab. "Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles". WIley Online Library.[27]
- Jonas G. Croissant, Yevhen Fatieiev, Abdulaziz Almalik, Niveen M. Khashab. "Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications". WIley Online Library.[28]
- Shahad K Alsaiari, Sachin Patil, Mram Alyami, Kholod O Alamoudi, Fajr A Aleisa, Jasmeen S Merzaban, Mo Li, and Niveen M Khashab. "Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework". ACS Publications.[29]
- Jonas G. Croissant, Xavier Cattoën, Michel Wong Chi Man, Jean-Olivier Durand and Niveen M. Khashab. "Syntheses and applications of periodic mesoporous organosilica nanoparticles". Nanoscale.[30]
- Jonas G Croissant, Dingyuan Zhang, Shahad Alsaiari, Jie Lu, Lin Deng, Fuyuhiko Tamanoi, Abdulaziz M AlMalik, Jeffrey I Zink, and Niveen M Khashab. "Protein-gold clusters-capped mesoporous silica nanoparticles for high drug loading, autonomous gemcitabine/doxorubicin co-delivery, and in-vivo tumor imaging". Journal of Controlled Release.[31]
- Mram Z Alyami, Shahad K Alsaiari, Yanyan Li, Somayah S Qutub, Fajr A Aleisa, Rachid Sougrat, Jasmeen S Merzaban, and Niveen M Khashab. "Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks". ACS Publications.[32]
