In 2019, Nnamdi Agbo debuted as CeeJay in Ordinary Fellows. In 2020, he played Wisdom in the series Crazy, Lovely, Cool, directed by Obi Emelonye which debuted on Netflix. In 2021, he gained mild prominence for portraying Mohammed Babangida in Badamasi: Portrait of a General, also directed by Emelonye. In 2022, Agbo wrote, produced and co-directed the short film Bound: Lost In The Moment, which addressed multiple personality disorder.[4]
After appearing in stage plays, Agbo got his big break, playing the lead character Omar a.k.a. Skipper in the Netflix original Hijack '93.[5] The film, directed by Robert O. Peters and written by Musa Jeffery David, is based on the 1993 Nigerian Airways hijack.[6] He also began starring as Prince Nwoye in the Showmax original epic drama series, Cheta'm in the same year. In 2025, he played a street thug, Soso in the Africa Magic film Everything Light Touches.[7] Both Cheta'm and Everything Light Touches earned nominations at the 2025 AMVCAs.[8] The latter won the award for 'Best MultiChoice Talent Factory'.[9] In May 2025, Agbo debuted in Fix+Foxy's global theatre play The Village,[10] featuring actors in Los Angeles, Mumbai, Istanbul and Lagos, and showing in Denmark.[11][12]