Nottingham Prognostic Index

Index for breast cancer surgery From Wikipedia, the free encyclopedia

The Nottingham prognostic index (NPI) is used to determine prognosis following surgery for breast cancer.[1][2] Its value is calculated using three pathological criteria: the size of the tumour; the number of involved lymph nodes; and the grade of the tumour.[1] It is calculated to select patients for adjuvant treatment.

Calculation

The index is calculated using the formula:[3]

NPI = [0.2 x S] + N + G

Where:

  • S is the size of the index lesion in centimetres[3]
  • N is the node status: 0 nodes = 1, 1-3 nodes = 2, >3 nodes = 3[3]
  • G is the grade of tumour: Grade I =1, Grade II =2, Grade III =3[3]

Interpretation

More information Score, 5-year survival ...
Score 5-year survival[4]
>/=2.0 to </=2.4 93%
>2.4 to </=3.4 85%
>3.4 to </=5.4 70%
>5.4 50%
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References

External links

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