NrsZ small RNA
From Wikipedia, the free encyclopedia
| NrsZ sRNA | |
|---|---|
Predicted secondary structure and sequence conservation of NrsZ small RNA | |
| Identifiers | |
| Rfam | RF02695 |
| Other data | |
| Domain | Bacteria |
| GO | GO:0071978 |
| SO | SO:0000370 |
| PDB structures | PDBe |
NrsZ (nitrogen regulated small RNA) is a bacterial small RNA found in the opportunistic pathogen Pseudomonas aeruginosa PAO1. Its transcription is induced during nitrogen limitation by the NtrB/C two-component system (an important regulator of nitrogen assimilation and swarming motility) together with the alternative sigma factor RpoN ( a global regulator involved in nitrogen metabolism). NrsZ by activating rhlA (a gene essential for rhamnolipids synthesis) positively regulates the production of rhamnolipid surfactants needed for swarming motility.[1]