Nuclear atypia
Abnormal appearance of cell nuclei
From Wikipedia, the free encyclopedia
Nuclear atypia refers to abnormal appearance of cell nuclei.[1] It is a term used in cytopathology and histopathology. Atypical nuclei are often pleomorphic.
Nuclear atypia can be seen in reactive changes, pre-neoplastic changes,[1] and malignancy. Severe nuclear atypia is, in most cases, considered an indicator of malignancy.
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