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Nuclear moulding

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In histopathology, nuclear moulding, also nuclear molding, is conformity of adjacent cell nuclei to one another.[1]

Micrograph of a small cell carcinoma showing cells with nuclear moulding. FNA specimen. Field stain.

It is a feature of small cell carcinomas and particularly useful for differentiation of small cell and non-small cell carcinomas, i.e. adenocarcinoma and squamous carcinoma.[2]

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