OPN1MW

Green-sensitive opsin is a protein that in humans is encoded by the OPN1MW gene.^[5] OPN1MW2 is a similar opsin.

AliasesOPN1MW, CBBM, CBD, COD5, GCP, GOP, OPN1MW1, opsin 1 (cone pigments), medium-wave-sensitive, opsin 1, medium wave sensitive

External IDsOMIM: 300821; MGI: 1097692; HomoloGene: 88332; GeneCards: OPN1MW; OMA:OPN1MW - orthologs

Chr.X chromosome (human)^[1]

End154,196,861 bp^[1]

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OPN1MW
Identifiers
Aliases	OPN1MW, CBBM, CBD, COD5, GCP, GOP, OPN1MW1, opsin 1 (cone pigments), medium-wave-sensitive, opsin 1, medium wave sensitive
External IDs	OMIM: 300821; MGI: 1097692; HomoloGene: 88332; GeneCards: OPN1MW; OMA:OPN1MW - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq28 Start 154,182,596 bp[1] End 154,196,861 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A7.3 Start 73,171,070 bp[2] End 73,194,366 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle appendix blood urinary bladder myometrium left adrenal cortex coronary artery left coronary artery right auricle of heart stomach Top expressed in neural layer of retina muscle of thigh retinal pigment epithelium epithelium of lens embryo outer nuclear layer knee joint soleus muscle skeletal muscle tissue quadriceps femoris muscle More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity photoreceptor activity signal transducer activity G protein-coupled photoreceptor activity identical protein binding Cellular component integral component of membrane plasma membrane membrane photoreceptor outer segment integral component of plasma membrane photoreceptor disc membrane Biological process positive regulation of cytokinesis signal transduction visual perception retinoid metabolic process response to stimulus G protein-coupled receptor signaling pathway phototransduction detection of visible light cellular response to light stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2652 14539 Ensembl ENSG00000268221 ENSMUSG00000031394 UniProt P04001 P0DN77 P0DN78 O35599 RefSeq (mRNA) NM_000513 NM_008106 RefSeq (protein) NP_001316996 NP_000504 NP_001041646 NP_000504.1 NP_001041646.1 NP_000504 NP_001041646 NP_000504.1 NP_001041646.1 NP_000504 NP_001041646 NP_032132 Location (UCSC) Chr X: 154.18 – 154.2 Mb Chr X: 73.17 – 73.19 Mb PubMed search [3] [4]
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The OPN1MW gene provides instructions for making an opsin pigment that is more sensitive to light in the middle of the visible spectrum (yellow/green light).^[6]