OR1E2

Olfactory receptor 1E2 is a protein that in humans is encoded by the OR1E2 gene.^[5][6][7]

AliasesOR1E2, OR17-135, OR17-93, OR1E4, OR1E7, OST529, OR17-136, olfactory receptor family 1 subfamily E member 2

External IDsMGI: 109315; HomoloGene: 128054; GeneCards: OR1E2; OMA:OR1E2 - orthologs

Chr.Chromosome 17 (human)^[1]

End3,433,841 bp^[1]

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OR1E2
Identifiers
Aliases	OR1E2, OR17-135, OR17-93, OR1E4, OR1E7, OST529, OR17-136, olfactory receptor family 1 subfamily E member 2
External IDs	MGI: 109315; HomoloGene: 128054; GeneCards: OR1E2; OMA:OR1E2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.2 Start 3,432,870 bp[1] End 3,433,841 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B4 Start 73,241,609 bp[2] End 73,246,777 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh superior frontal gyrus lymph node Top expressed in spermatocyte More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity signaling receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process sensory perception of chemical stimulus sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8388 258925 Ensembl ENSG00000127780 ENSMUSG00000062128 UniProt P47887 Q7TRX9 RefSeq (mRNA) NM_003554 NM_146923 RefSeq (protein) NP_003545 NP_667134 Location (UCSC) Chr 17: 3.43 – 3.43 Mb Chr 11: 73.24 – 73.25 Mb PubMed search [3] [4]
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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[7]