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OSBPL11

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Oxysterol-binding protein-related protein 11 is a protein that in humans is encoded by the OSBPL11 gene.[5]

AliasesOSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292, oxysterol binding protein like 11
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OSBPL11
Identifiers
AliasesOSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292, oxysterol binding protein like 11
External IDsOMIM: 606739; MGI: 2146553; GeneCards: OSBPL11
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022776

NM_176840

RefSeq (protein)

NP_073613

NP_789810

Location (UCSC)Chr 3: 125.53 – 125.6 MbChr 16: 33.01 – 33.06 Mb
PubMed search[3][4]
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Function

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid transfer proteins.[6] The protein product of the gene, ORP11, contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.[5] It forms homo-dimers with the ORP9, the product of the OSBPL9 gene.[7]

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