OSR2 (gene)

PDBOrtholog search: PDBe RCSB

AliasesOSR2, odd-skipped related transciption factor 2

External IDsOMIM: 611297; MGI: 1930813; HomoloGene: 14200; GeneCards: OSR2; OMA:OSR2 - orthologs

Chr.Chromosome 8 (human)^[1]

OSR2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2EE8
Identifiers
Aliases	OSR2, odd-skipped related transciption factor 2
External IDs	OMIM: 611297; MGI: 1930813; HomoloGene: 14200; GeneCards: OSR2; OMA:OSR2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q22.2 Start 98,944,403 bp[1] End 98,952,104 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 B3.1|15 14.46 cM Start 35,296,244 bp[2] End 35,303,451 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva body of uterus canal of the cervix left uterine tube seminal vesicula right ovary urethra decidua ectocervix right uterine tube Top expressed in genital tubercle female external genitalia uterus paramesonephric duct ileum intestinal villus vas deferens eyelid right kidney jejunum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding protein binding nucleic acid binding sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding Cellular component nucleus Biological process negative regulation of transcription by RNA polymerase II metanephros development mesonephros development chondrocyte differentiation positive regulation of cell population proliferation positive regulation of gene expression cell differentiation positive regulation of bone mineralization osteoblast proliferation embryonic forelimb morphogenesis embryonic hindlimb morphogenesis embryonic skeletal limb joint morphogenesis middle ear morphogenesis odontogenesis embryonic digit morphogenesis positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II embryonic skeletal system morphogenesis positive regulation of epithelial cell proliferation roof of mouth development embryonic skeletal joint morphogenesis head development bone morphogenesis eyelid development in camera-type eye embryonic skeletal joint development embryo development ending in birth or egg hatching urogenital system development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116039 107587 Ensembl ENSG00000164920 ENSMUSG00000022330 UniProt Q8N2R0 Q91ZD1 RefSeq (mRNA) NM_001142462 NM_001286841 NM_053001 NM_001394683 NM_054049 NM_001368665 RefSeq (protein) NP_001135934 NP_001273770 NP_443727 NP_473390 NP_001355594 Location (UCSC) Chr 8: 98.94 – 98.95 Mb Chr 15: 35.3 – 35.3 Mb PubMed search [3] [4]
Wikidata
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Protein odd-skipped-related 2 is a protein that in humans is encoded by the OSR2 gene.^[5] In mice, it is involved in the development of the palate and in suppressing the formation of teeth after the eruption of adult teeth.