OSS-128167

OSS-128167 is a drug which acts as a sirtuin-6 (SIRT6) inhibitor. It has pro-inflammatory effects and accelerates cellular aging; however, it shows anti-viral and anti-cancer properties which are useful in research, and has also demonstrated potential medical applications for SIRT6 inhibitors such as in the treatment of some forms of asthma.^{[1][2][3][4][5]}

Drug classSirtuin-6 (SIRT6) inhibitor

CAS Number

• 887686-02-4

PubChem CID

• 6496840

ChemSpider

• 4997276

Quick facts Clinical data, Drug class ...

OSS-128167

Clinical data
Drug class	Sirtuin-6 (SIRT6) inhibitor
Identifiers
IUPAC name 5-[[3-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid
CAS Number	887686-02-4
PubChem CID	6496840
ChemSpider	4997276
ChEMBL	ChEMBL1588664
Chemical and physical data
Formula	C19H14N2O6
Molar mass	366.329 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC(=CC(=C1)NC(=O)C2=CC=CO2)C(=O)NC3=CC(=C(C=C3)O)C(=O)O
InChI InChI=1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26) Key:HTJWLEGCECXGSQ-UHFFFAOYSA-N

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