Obexelimab

Experimental drug From Wikipedia, the free encyclopedia

Obexelimab is an experimental drug developed to treat IgG4-related disease and lupus. It works as a "bifunctional, non-cytolytic, humanised monoclonal antibody that binds CD19 and Fc gamma receptor IIb to inhibit B cells, plasmablasts, and CD19-expressing plasma cells."[1][2]

TargetCD19 and Fc gamma receptor IIb
Other namesAMG 729
Legal status
  • Investigational
Quick facts Monoclonal antibody, Type ...
Obexelimab
Monoclonal antibody
Type?
TargetCD19 and Fc gamma receptor IIb
Clinical data
Other namesAMG 729
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
DrugBank
UNII
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