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Ocedurenone

Chemical compound From Wikipedia, the free encyclopedia

Ocedurenone, formerly known as KBP-5074,[1] is a nonsteroidal, selective mineralocorticoid receptor antagonist that is being developed to treat hypertension in patients with chronic kidney disease with less risk of hyperkalemia than existing treatments.[2][3] In 2023, KPB Biosciences entered into talks to sell the drug to Novo Nordisk for up to USD$1.3 billion. It is a small molecule drug administered orally and is in a Phase III trial that is scheduled to complete in 2024.[4][5]

Other namesKBP-5074
Legal status
  • Investigational
Quick facts Clinical data, Other names ...
Ocedurenone
Clinical data
Other namesKBP-5074
Legal status
Legal status
  • Investigational
Identifiers
  • 4-[(3S,3aR)-3-Cyclopentyl-7-(4-hydroxypiperidine-1-carbonyl)-3,3a,4,5-tetrahydropyrazolo[3,4-f]quinolin-2-yl]-2-chlorobenzonitrile
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC28H30ClN5O2
Molar mass504.03 g·mol−1
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