Olfactory marker protein

Protein family From Wikipedia, the free encyclopedia

In molecular biology, olfactory marker protein is a protein involved in signal transduction. It is a highly expressed, cytoplasmic protein found in mature olfactory sensory receptor neurons of all vertebrates. OMP is a modulator of the olfactory signal transduction cascade. The crystal structure of OMP reveals a beta sandwich consisting of eight strands in two sheets with a jelly-roll topology.[1] Three highly conserved regions have been identified as possible protein–protein interaction sites in OMP, indicating a possible role for OMP in modulating such interactions, thereby acting as a molecular switch.[2]

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olfactory marker protein
Identifiers
SymbolOMP
NCBI gene4975
HGNC8136
OMIM164340
RefSeqNM_006189
UniProtP47874
Other data
LocusChr. 11 q14-q21
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StructuresSwiss-model
DomainsInterPro
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Quick facts Identifiers, Symbol ...
Olfactory marker protein
solution structure of olfactory marker protein from rat
Identifiers
SymbolOlfactory_mark
PfamPF06554
InterProIPR009103
SCOP21jyt / SCOPe / SUPFAM
Available protein structures:
PDB  IPR009103 PF06554 (ECOD; PDBsum)  
AlphaFold
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