The village was first mentioned in 1554 as Oitkensplate, and means "shoal of Oltken (person)".[3] Ooltgensplaat developed after the Het Oudeland polder was created between 1481 and 1483. The village has a harbour canal to the Volkerak. Ooltgensplaats became strategically important during the Eighty Years' War because it controlled the access to the Volkerak.[4]
The Dutch Reformed church is an aisleless L-shaped church which was built in 1847 as a replacement of the 16th century church. The former town hall is a building in mannerist style built between 1617 and 1618. It was restored between 1938 and 1939, and many of the alterations from 1839 were undone.[4]
Fort Prins Hendrik was built as Fort Duquesne by the French. It is a square fortress surrounded by a moat with bastions on the corners. L-shaped barracks were added between 1880 and 1883. The fortress was decommissioned in 1928. In 1969, it was used as a holiday resort.[4] The company went bankrupt in 2014, and in 2018, the fort and surrounding area was bought by the municipality.[5]
Ooltgensplaat was home to 1,583 people in 1840.[5] It was a separate municipality until 1966, when it became part of Oostflakkee.[6] In 2013, it became part of the municipality of Goeree-Overflakkee.[5]