Ophidascaris robertsi

Reported infections in pythons include Antaresia childreni (children's python), Aspidites melanocephalus (black-headed python), Aspidites ramsayi (woma python), and Morelia spilota (carpet python).^[6] There are also reports of infections in a sugar glider (Petaurus breviceps), a koala (Phascolarctos cinereus), a bandicoot (Perameles nasuta) and in other small to medium-sized marsupial species.^[7][8][9] One case report of zoonotic infection in a human brain from Australia during 2021–22 was reported in August 2023.^[4][10]

A 2021 study on host loss in parasite species used Ophidascaris robertsi as one of the subject taxa.^[11]

In June 2022, a neurosurgeon in an Australian hospital found a roundworm in a woman's brain while investigating her mysterious symptoms.^[4] The woman initially reported diarrhea and abdominal pain, along with night sweats and dry cough, and was originally diagnosed with a rare lung infection.^[12] Though her symptoms improved with treatment, she subsequently returned with symptoms of fever and cough, resulting in an additional diagnosis of a blood disorder. Worsening symptoms of forgetfulness and depression resulted in an MRI that revealed a brain lesion. The biopsy resulted in the discovery and extraction of the live worm.^[12] This was the first known instance of such an occurrence, as this type of worm had never been identified as a human parasite before.^[4][10][13] The woman, who lived near carpet python habitat and foraged for native vegetation to cook, was believed to have been exposed by consuming the roundworm's eggs. These eggs, which were commonly shed in snake droppings due to the snakes' diet of infected animals, likely contaminated the grass eaten by small mammals.^[4][13][3] Doctors theorize that the various symptoms experienced by the patient resulted from the migration of the parasitic eggs and larva from the bowel, through various other organs, before arriving in the brain.^[12]