Ortho-Bromophenylpiperazine

ortho-Bromophenylpiperazine (oBPP), also known as 2-bromophenylpiperazine (2-BPP), is a monoamine releasing agent of the phenylpiperazine family.^[1] It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC₅₀Tooltip half-maximal effective concentration values of 132 nM for serotonin, 33 nM for norepinephrine, and 250 nM for dopamine in rat brain synaptosomes.^[1] The drug was first described in the scientific literature by 2012.^[1]

Other namesoBPP; 2-Bromophenylpiperazine; 2-BPP; 2-Bromo-PP

Drug classSerotonin–norepinephrine–dopamine releasing agent

CAS Number

• 1011-13-8

PubChem CID

• 2757153

Quick facts Clinical data, Other names ...

ortho-Bromophenylpiperazine

Clinical data
Other names	oBPP; 2-Bromophenylpiperazine; 2-BPP; 2-Bromo-PP
Drug class	Serotonin–norepinephrine–dopamine releasing agent
Identifiers
IUPAC name 1-(2-bromophenyl)piperazine
CAS Number	1011-13-8
PubChem CID	2757153
ChemSpider	2037913
CompTox Dashboard (EPA)	DTXSID60373747
ECHA InfoCard	100.199.072
Chemical and physical data
Formula	C10H13BrN2
Molar mass	241.132 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCN1)C2=CC=CC=C2Br
InChI InChI=1S/C10H13BrN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 Key:JVTRURBMYILQDA-UHFFFAOYSA-N

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