Oxiperomide

Oxiperomide
Clinical data
Routes of; administration	Oral
Identifiers
	IUPAC name 3-[1-(2-phenoxyethyl)piperidin-4-yl]-1H-benzimidazol-2-one;
CAS Number	5322-53-2;
PubChem CID	68634;
ChemSpider	61893;
UNII	WRO75M6RW2;
KEGG	D02676;
ChEMBL	ChEMBL2059304;
CompTox Dashboard (EPA)	DTXSID30201306 ;
Chemical and physical data
Formula	C20H23N3O2
Molar mass	337.423 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCOC4=CC=CC=C4;
	InChI InChI=1S/C20H23N3O2/c24-20-21-18-8-4-5-9-19(18)23(20)16-10-12-22(13-11-16)14-15-25-17-6-2-1-3-7-17/h1-9,16H,10-15H2,(H,21,24); Key:NVDBBGBUTKLRSN-UHFFFAOYSA-N;

Oxiperomide is an antipsychotic.^[1] Clinical trials demonstrated that it can reduce dyskinesia in patients with Parkinson's disease who are taking dopamine agonists without increasing Parkinsonian symptoms. It does this by selectively antagonizing dopamine receptors.^[2]^[3] Further development of this drug is not available. It appears to have never been marketed.

References

Clinical data

Routes of administration	Oral
Identifiers
IUPAC name 3-[1-(2-phenoxyethyl)piperidin-4-yl]-1H-benzimidazol-2-one
CAS Number	5322-53-2
PubChem CID	68634
ChemSpider	61893
UNII	WRO75M6RW2
KEGG	D02676
ChEMBL	ChEMBL2059304
CompTox Dashboard (EPA)	DTXSID30201306
Chemical and physical data
Formula	C₂₀H₂₃N₃O₂
Molar mass	337.423 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCOC4=CC=CC=C4
InChI InChI=1S/C20H23N3O2/c24-20-21-18-8-4-5-9-19(18)23(20)16-10-12-22(13-11-16)14-15-25-17-6-2-1-3-7-17/h1-9,16H,10-15H2,(H,21,24) Key:NVDBBGBUTKLRSN-UHFFFAOYSA-N