PABPC5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. [5]

AliasesPABPC5, PABP5, poly(A) binding protein cytoplasmic 5
End91,438,584 bp[1]
Quick facts Identifiers, Aliases ...
PABPC5
Identifiers
AliasesPABPC5, PABP5, poly(A) binding protein cytoplasmic 5
External IDsOMIM: 300407; MGI: 2136401; HomoloGene: 5857; GeneCards: PABPC5; OMA:PABPC5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080832

NM_053114

RefSeq (protein)

NP_543022

NP_444344

Location (UCSC)Chr X: 91.43 – 91.44 MbChr X: 118.84 – 118.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010].

References

Further reading

Related Articles

Wikiwand AI