PAX4
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene.[5][6][7]
External IDsOMIM: 167413; MGI: 97488; HomoloGene: 4515; GeneCards: PAX4; OMA:PAX4 - orthologs
Function
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.[5]