PAX4

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene.[5][6][7]

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PAX4
Identifiers
AliasesPAX4, KPD, MODY9, paired box 4
External IDsOMIM: 167413; MGI: 97488; HomoloGene: 4515; GeneCards: PAX4; OMA:PAX4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006193
NM_001366110
NM_001366111

NM_001159925
NM_001159926
NM_011038

RefSeq (protein)

NP_006184
NP_001353039
NP_001353040

NP_001153397
NP_001153398
NP_035168

Location (UCSC)Chr 7: 127.61 – 127.62 MbChr 6: 28.44 – 28.45 Mb
PubMed search[3][4]
Wikidata
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Function

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.[5]

See also

References

Further reading

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