PDCD7

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.^[5][6]

AliasesPDCD7, ES18, HES18, programmed cell death 7, 59K

External IDsOMIM: 608138; MGI: 1859170; HomoloGene: 4170; GeneCards: PDCD7; OMA:PDCD7 - orthologs

Chr.Chromosome 15 (human)^[1]

End65,133,808 bp^[1]

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PDCD7
Identifiers
Aliases	PDCD7, ES18, HES18, programmed cell death 7, 59K
External IDs	OMIM: 608138; MGI: 1859170; HomoloGene: 4170; GeneCards: PDCD7; OMA:PDCD7 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q22.31 Start 65,117,379 bp[1] End 65,133,808 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 C Start 65,253,386 bp[2] End 65,266,925 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte buccal mucosa cell nipple superior surface of tongue tendon of biceps brachii thymus external globus pallidus nasal epithelium tail of epididymis medulla oblongata Top expressed in primary oocyte secondary oocyte zygote spermatocyte neural layer of retina muscle of thigh epiblast soleus muscle genital tubercle corneal stroma More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 10081 50996 Ensembl ENSG00000090470 ENSMUSG00000041837 UniProt Q8N8D1 Q9WTY1 RefSeq (mRNA) NM_005707 NM_016688 RefSeq (protein) NP_005698 n/a Location (UCSC) Chr 15: 65.12 – 65.13 Mb Chr 9: 65.25 – 65.27 Mb PubMed search [3] [4]
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This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.^[6]