PEPA (drug)

PEPA
Clinical data
Other names	PEPA
Legal status
Legal status	US: Investigational New Drug;
Identifiers
	IUPAC name 2-[2,6-difluoro-4-({2-[(phenylsulfonyl)amino]ethyl}thio)phenoxy]acetamide;
CAS Number	141286-78-4 ;
PubChem CID	6603828;
ChemSpider	5036138 ;
UNII	8S4PR7A8JS;
CompTox Dashboard (EPA)	DTXSID60424960 ;
Chemical and physical data
Formula	C16H16F2N2O4S2
Molar mass	402.43 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=CC=C(C=C1)S(=O)(=O)NCCSC2=CC(=C(C(=C2)F)OCC(=O)N)F;
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PEPA is a sulfonamide AMPA receptor positive allosteric modulator,^[1]^[2] which is up to 100 times more potent than aniracetam in vitro.^[3] It produces memory-enhancing effects in rats when administered intravenously.^[4]