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PHF2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

PHD finger protein 2 is a protein that in humans is encoded by the PHF2 gene.[5]

AliasesPHF2, CENP-35, GRC5, JHDM1E, PHD finger protein 2, KDM7C
External IDsOMIM: 604351; MGI: 1338034; GeneCards: PHF2
PDBOrtholog search: PDBe RCSB
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PHF2
Identifiers
AliasesPHF2, CENP-35, GRC5, JHDM1E, PHD finger protein 2, KDM7C
External IDsOMIM: 604351; MGI: 1338034; GeneCards: PHF2
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005392
NM_024517

NM_011078

RefSeq (protein)

NP_005383

NP_035208

Location (UCSC)Chr 9: 93.58 – 93.68 MbChr 13: 48.96 – 49.02 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure.

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