PHPT1

PHPT1
Identifiers
Aliases	PHPT1, CGI-202, HEL-S-132P, HSPC141, PHP14, phosphohistidine phosphatase 1, PHP
External IDs	OMIM: 610167; MGI: 1922704; GeneCards: PHPT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2AI6, 2HW4, 2NMM, 2OZW, 2OZX
Enzyme activity
Gene location (Human)
Chr.	Chromosome 9 (human)
End	136,851,027 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	25,465,236 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; muscle of thigh; ; anterior pituitary; ; right adrenal gland; ; right adrenal cortex; ; right auricle of heart; ; body of pancreas; ; right hemisphere of cerebellum; ; left adrenal cortex; ; C1 segment;
	Top expressed in
	lens; ; yolk sac; ; quadriceps femoris muscle; ; neural tube; ; cerebellum; ; olfactory bulb; ; muscle tissue; ; neural layer of retina; ; cerebellar cortex; ; skeletal muscle tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium channel inhibitor activity; phosphoprotein phosphatase activity; hydrolase activity; transmembrane transporter binding; protein binding; protein histidine phosphatase activity;
Cellular component	cytoplasm; cytosol; extracellular exosome;
Biological process	negative regulation of lyase activity; positive regulation of insulin secretion involved in cellular response to glucose stimulus; protein dephosphorylation; regulation of actin cytoskeleton reorganization; peptidyl-histidine dephosphorylation; negative regulation of ATP citrate synthase activity; positive regulation of cell motility; negative regulation of T cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	29085
	75454
	ENSG00000054148
	ENSMUSG00000036504
	Q9NRX4
	Q9DAK9
	NM_001135860; NM_001135861; NM_001287342; NM_001287343; NM_014172
	NM_029293
	NP_001129333; NP_001274271; NP_001274272; NP_054891
	NP_083569
	Wikidata
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