PIGN (gene)

From Wikipedia, the free encyclopedia

AliasesPIGN, MCAHS, MCAHS1, MCD4, MDC4, PIG-N, phosphatidylinositol glycan anchor biosynthesis class N
End62,187,118 bp[1]
PIGN
Identifiers
AliasesPIGN, MCAHS, MCAHS1, MCD4, MDC4, PIG-N, phosphatidylinositol glycan anchor biosynthesis class N
External IDsOMIM: 606097; MGI: 1351629; HomoloGene: 6330; GeneCards: PIGN; OMA:PIGN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012327
NM_176787

NM_013784

RefSeq (protein)

NP_036459
NP_789744

n/a

Location (UCSC)Chr 18: 61.91 – 62.19 MbChr 1: 105.45 – 105.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphatidylinositol glycan anchor biosynthesis, class N is a protein that in humans is encoded by the PIGN gene.[5]

This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor.

Clinical aspect

References

Further reading

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